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The Pirates started the season with wins over West Carolina and NC State, but fell to South Carolina last week. That loss helped show East Carolina isn’t ready to compete with the big boys and it will be a significant underdog.Virginia Tech has designs of being a force in ACC play, and needs to win this one comfortable to be considered a factor.... 

It’s been a tough start to the 2016 for Notre Dame, facing two fellow Top 25 teams in the first three games so a win this week at home against Duke will be essential.Duke is also 1-2 on the year so far and has lost two in a row coming into this one including a 24-13 loss to Northwestern last week. An upset here would be huge but it seems unlikely.... 

The Oregon Ducks return home for Week 4 to host the Colorado Buffaloes, each team hoping to rebound off their first loss of the season. Historically, this has been a matchup owned by the Ducks, winning 12 of 20 contests. Oregon has beaten the Buffaloes in six straight meetings, including going into Boulder last year and trouncing them by 17-points. Colorado will go for the upset looking to put an end to that streak, while the Ducks are in position to extend it.... 

Darrell Hazell probably needs five wins if he wants to remain employed as the head coach of the Purdue Boilermakers and this Week 4 College Football matchup against the Nevada Wolfpack is likely the only one he will be favored to win the rest of the season. Although Nevada got hammered by Notre Dame two weeks ago, the Wolfpack are a pretty competent Mountain West team and will give the Boilermakers all they can handle. Will Purdue get its second win of the season or will Nevada be able to pull o... 

Two of the better teams in the Mountain West will look to start conference play on a winning note when the Air Force Falcons travel west to face the Utah State Aggies in a late Saturday night game. Air Force has been flying high to start the season, cruising to easy wins against Abilene Christian and Georgia State, while Utah State has only fallen to USC up to this point. These teams are both unheralded, but legitimate contenders for the Mountain West crown and whoever wins this matchup will put themselves in good shape.... 

It’s a crime that the Wisconsin Badgers and Michigan State Spartans haven’t opposed one another on the college gridiron since 2012, but come this Saturday, the rivalry will be forced to write yet another chapter after leaving its audience in suspense the last three years. This is the first of a hellacious two game roady for the Badgers who have to go to the Big House next week. Off a dominant performance last week, Sparty will look to get Wiscy’s road trip started off on the wrong foot.... 

The No. 4 ranked Michigan Wolverines will attempt to take their third straight in the recent rivalry with the Penn State Nittany Lions in Week 4 when the rivals open up Big Ten play Saturday afternoon in the Big House. Jim Harbaugh’s squad got a scare from a game Colorado squad last week but rattled off 38 straight points to secure win No. 3. Will James Franklin’s squad be able to move the chains enough to match points with the efficient Wolverines? Let’s dig in and find out.... 

This is one of your classic early season matchups where a lesser team gets paid big bucks to travel and take a thorough beating. But, when the Kent State Golden Flash head to Tuscaloosa to play the Alabama Crimson Tide in Week 4, it’ll have special meaning for Nick Saban, a Kent State graduate. As for his players, it’ll have special meaning to them, too, as the starters will get much needed rest after they rally back to beat No. 19 Ole Miss in Week 3.... 

The Stanford Cardinals made a statement on Saturday toppling USC. They are primed to carry that success into Week 4’s matchup against the UCLA Bruins. The Cardinals have been a major issue for the Bruins under Jim Mora. In fact, the last time UCLA got the win over Stanford predates Mora’s stint at the helm by a couple of years. After the hiccup in Week 1 against Texas A&M, the Bruins need this win. Now would be a great time to end the winless streak against Stanford. Meanwhile, Stanford will... 

Off a soul crushing defeat to reigning FCS champ North Dakota State, the Iowa Hawkeyes will look to pick up the pieces on the road where they’ll kick off Big Ten play against the Rutgers Scarlet Knights. This Week 4 brawl marks the first time these programs will have run up against one another on the college gridiron as conference rivals. While Iowa will no doubt be looking to rebound, they’ll be opposing an amped up home team that comes off an exhilarating come-from-behind win over New Mexico.... 

The Mississippi Rebels will try and turn their season around on Saturday as they host the Georgia Bulldogs in a Week 4 matchup that can be seen on ESPN. The Rebels could be 3-0 instead of 1-2 but they have no defense as they blew a big lead to Florida State in Week 1 and last week they blew a 21-point lead to Alabama. The Rebels are still getting respect from oddsmakers as Mississippi is listed as a 7-point home favorite against the unbeaten Bulldogs.... 

The Tennessee Volunteers will look to end their recent misery against the Florida Gators when the teams meet in Week 4 action on Saturday in a matchup of Top 20 teams on CBS. The Gators have won the last 11 games against the Volunteers including 28-27 at home last season. The last win for Tennessee in this series was in 2004 when the Vols won 30-28. Oddsmakers like the chances for Tennessee to break the losing streak on Saturday as the Volunteers are listed as a 7-point favorite.... 

The BYU Cougars have been a gritty bunch under first year head coach Kalani Sitake beating Arizona and hanging tough with both Utah and UCLA. They’ll aim for a fourth straight pointspread cover and a possible win against the West Virginia Mountaineers when the teams meet in Landover Week 4. The Cougars are the defensive dog in this matchup but the ‘Neers offense will be the best it’s run up against to date.... 

Texas-San Antonio fought the Arizona State Sun Devils hard, but ultimately Arizona State pulled the game out in the fourth quarter. Still, that was a game the Sun Devils were supposed to win by a considerable margin. They’ll now head back home to open up the Pac-12 portion of their schedule in Week 4 against the California Golden Bears. California got the win over the Sun Devils last season in a shootout and will be on the hunt for their second straight upset after toppling Texas in Week 3.... 

The UNLV Rebels are in the second year of the Tony Sanchez era and are still waiting to see a return on their investment. The school made a big gamble when it hired the coach from powerhouse Bishop Gorman High School as Sanchez had never coached at the collegiate level prior to the hire. This Week 4 college football matchup against the Idaho Vandals is one of those games that he must win in order for the administration to continue to have faith in him.... 

It’s been a magical year so far for the Houston Cougars. An early season upset of Oklahoma combined with a meteoric rise to the No. 6 spot in the AP poll has given the Cougars the best shot so far of any mid-major team to make the College Football Playoff. However, Houston can’t afford to slip up somewhere along the way and must stay focused throughout the season. In College Football Week 4, they will travel to San Marcos to take on the Texas State Bobcats.... 

The third year is where coaches usually turn the corner if they are going to, but that hasn’t happened yet for Derek Mason and the Vanderbilt Commodores. Vandy lost a rock fight to South Carolina to kick off the season and got housed against Georgia Tech last week. In College Football Week 4, the Commodores will have a chance to get their second win of the season when they play the Western Kentucky Hilltoppers away from home.... 

The Baylor Bear’s offensive machine has yet to get off the ground through the first three weeks of the season evidenced by each game combining to go under the total. That trend could come to a screeching halt here in Week 4 when the Oklahoma State Cowboys and their defense that just gave up 38 points to PITT pays Waco a visit for the game that kicks off each school’s respective Big 12 campaign.... 

A big one is set to go down in the SEC West late Saturday evening when a pair of 3-0 teams in the Arkansas Razorbacks and Texas AM Aggies throw down in Jerry’s World for the rights of playing second fiddle to Alabama within the division. These squads played to an overtime thriller in Fayetteville last season that saw the Aggies run their win streak to four straight in the recent series, so another doozy is likely in store Week 4.... 

The Clemson Tigers will try and do something on Thursday night that they have not done since 2003 and that is get a win in Atlanta against the Georgia Tech Yellow Jackets. The Tigers come into this Week 4 matchup unbeaten and ranked in the top 5 in the country while the Yellow Jackets are also unbeaten but unranked. The Tigers opened up as 9.5-point favorites in this contest that can be seen on ESPN.... 

Something has to give on Saturday as the weak offense of the South Carolina Gamecocks goes against the pathetic defense of the Kentucky Wildcats. This Week 4 matchup that can be seen on SEC Network matches up the South Carolina offense that is averaging just 15.7 points per game against a Kentucky defense that is giving up 43.7 points per contest. This series has been high scoring of late with 8 of the last 9 meetings going over the total.... 

The Auburn Tigers will try and turn their season around on Saturday as they host the LSU Tigers on ESPN. Auburn has dropped two of their first three games and head coach Gus Malzahn is feeling the heat. On the other side, LSU hasn’t been that much better as they come into this Week 4 matchup at 2-1 but 0-3 ATS. This game could turn into a defensive struggle as LSU has gone under in all three of their games this season while Auburn has gone under in two of their three contests.... 

The TCU Horned Frogs will look to snag their first cover of the season under the Friday night lights when they pay a visit to the SMU Mustangs for the program’s annual in-state rivalry game. The Mustangs have paid out each of the first three weeks of the season, but they’ll be up against it in this one considering they’ve failed to stick within 19 of their opponent the last three meetings. It certainly doesn’t look good on paper or from a historical perspective, but will the Horned Frogs be 100 ... 

The Dino Babers era is off to a rocky start in Syracuse. Although the Syracuse Orange have been able to score points at a much higher clip than they did last season, the defense has been eviscerated the last two games. Now Syracuse has to travel to take on the Connecticut Huskies in a much different test before ACC play starts. This battle between former Big East foes will be one of the undercards on a full plate of Week 4 college football action.... 

The Minnesota Golden Gophers are looking to go through their non-conference schedule undefeated before entering the grind that is Big Ten play and the Colorado State Rams are standing in their way. This Week 4 college football game will be important for both teams as they hope to enter their conference schedules on a winning note and get to half the wins needed to get to the college football postseason, provided the NCAA doesn’t take five-win teams again in 2016....