Although the Los Angeles Chargers are 5-3 and the San Francisco 49ers are 4-4, the 49ers are seen as much more of a postseason contender. San Francisco has dealt with a number of injuries once again, hurting this team through the first half of the regular season. They are still without a handful of starters on defense, but they have the second lowest odds to win the NFC behind Philadelphia and are a team that no one wants to take on in the playoffs.
The San Francisco 49ers have had two weeks to prepare for the Los Angeles Chargers and are sizeable favorites at home on Sunday Night Football . The Niners and Chargers will meet on Sunday, November 13, 2022, at 8:20 p.m. ET on NBC from Levi’s Stadium in Santa Clara, California.
NFL Week 10 Betting Odds
Los Angeles Chargers +7
San Francisco 49ers -7
Total 46
Money Line: Chargers +252, 49ers -310
Odds Analysis
Initially, the NFL betting odds had San Francisco favored by six points on Sunday Night Football. However, the line has since moved to seven points, as action has come in on the Niners. The total has dropped from 46.5 to 45.5 and might fall even further before kickoff.
Los Angeles Chargers
Once again, injuries have really hurt the Los Angeles Chargers . For the second straight season, the Chargers have one of the best teams in the league on paper. However, top cornerback J.C. Jackson only played in a few games before suffering a season-ending knee injury, and All-Pro players Rashawn Slater and Joey Bosa are on injured reserve. To make matters worse, No. 1 receiver Keenan Allen has only played in two games because of a lingering hamstring injury, and now No. 2 receiver Mike Williams is out due to an ankle issue.
Third-year quarterback Justin Herbert has struggled as a result of the injuries. Herbert is completing 66.4% of his passes for 2,254 yards (6.4 YPA) with 13 touchdowns and five interceptions. Running back Austin Ekeler has become his favorite target due to the injuries, and Ekeler has 60 receptions for 381 yards and four touchdowns. He has run for 427 yards and six touchdowns too, while averaging 4.4 YPC.
The Chargers were supposed to be much better on defense with the addition of Khalil Mack and J.C. Jackson. Mack is the team’s best pass rusher with six sacks and two forced fumbles, but Jackson’s injury really hurt the potential of this secondary. That is part of why LA ranks 30th in scoring defense, allowing 25.8 PPG. However, the bigger concern is this front seven aside from Mack. The Chargers are conceding 5.7 YPC (worst in the NFL), and that’s a huge problem against a run heavy team like San Francisco.
VIDEO San Francisco 49ers
Usually trade deadline moves don’t amount to much, but San Francisco’s decision to trade for Christian McCaffrey may end up being as important as the Los Angeles Rams’ move to trade for Odell Beckham Jr. last year. McCaffrey is the prototype back for Kyle Shanahan’s offense as he can carry the ball in between the tackles and be used as a receiver out of the backfield. We saw his potential two weeks ago against the Los Angeles Rams when he became just the third player in NFL history to throw, catch, and run for a touchdown in the same game. McCaffrey has had more time to learn the offense after a bye week, so he could post big numbers.
That will certainly help Jimmy Garoppolo too. It’s become painfully clear that Garoppolo is a game manager under center, and the addition of McCaffrey gives him someone to dump the ball off to when he’s in trouble. If Deebo Samuel and George Kittle can stay healthy over the second half of the season, this offense could really explode.
San Francisco has the best defense in the league. The 49ers are allowing 285.9 YPG, and that’s despite being without Javon Kinlaw, Azeez Al-Shaair, and Emmanuel Moseley. Arik Armstead, Dre Greenlaw, and Jason Verrett are all questionable for this game as well, so this game could be higher scoring than expected.
Chargers at 49ers Free Pick
This could be a rout as San Francisco has the potential to run all over the Chargers’ front seven with a healthy offensive line. If LA can’t stop the run, Herbert will have to throw for at least 300 yards and a few scores to pull off the upset.
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