Cardinals at Panthers NFL Week 16 Betting Lines

Arizona Cardinals NFL Week 16 Betting Lines

After going into their Week 11 bye off a dominant 31-6 victory over the New York Jets, the Arizona Cardinals appeared in control of the NFC West with some cushion to work with. Fast forward four weeks, and Jonathan Gannon’s squad now trails both the Seattle Seahawks and Los Angeles Rams—highlighting how quickly fortunes can change in the NFL. The slide would’ve been worse if not for Arizona halting the skid last Sunday with a 30-17 win and NFL odds cover against the New England Patriots. While the Cardinals covered as 6-point favorites, their fourth-quarter effort left much to be desired, after allowing the Patriots to do a bulk of their damage after easing off the gas. Inexcusable for a team battling for its playoff life, as point differentials could play a crucial role in tiebreakers down the stretch. With the NFC West title likely the Cardinals’ clearest path to the postseason, urgency is at an all-time high heading into a critical Week 16 road matchup against the Carolina Panthers. Carolina has been feisty recently, so Arizona cannot afford to overlook them with a pivotal showdown against the Rams looming the following week. Action reports from the online sportsbook expect all hands to be on deck as the Redbirds aim to keep their playoff hopes alive.

Though the bleeding was stopped, the Cardinals odds to win the big game still fattened up to 150-1 from 110-1, while their longshot odds of winning the NFC remained 50-1. Now one game out in the NFC West standings, Arizona shortened to +550 from +700 to take home division bragging rights, while its adjusted in-season win total odds held firm at 8.5 with slightly heavier vig now attached to the under. The Cardinals not making the playoffs fell to -750 from -1000, while the “Yes” shortened to +500 after a $100 investment offered up a $650 return on investment heading into last week’s crucial home tilt with the Patriots.

NFL Week 16 Betting Lines

Arizona Cardinals -4

Carolina Panthers +4

Over/Under: 47.5

Money Line: Cardinals -216, Panthers +181

Arizona Cardinals Week 16 Matchup

On Sunday, December 22, 2024, the Arizona Cardinals will take on the Carolina Panthers from Bank of America Stadium in Charlotte, NC. Kickoff time is set for 1 p.m. ET with television coverage on FOX. The lookahead NFL Week 16 betting lines hit the board with the Cardinals installed 4.5-point road favorites and the total lined 46.5. Linemakers are yet to move off the opener with the Cardinals only being aligned with 50 percent of the bets and 55 percent of the money, though it should be noted some -4 has started to pop at other outlets. Evidently, customers betting on the NFL with cryptocurrency have taken a bearish stance on Arizona winning by margin in this must-win spot. Understandable considering James Conner and his mates stand 2-4 straight up (SU) and 4-2 against the spread (ATS) away from the desert with it dropping a 16-6 decision in Seattle the lone instance it was installed a road chalk. Total bettors do however appear to be bullish of points being scored with the number to beat up a full point to 47.5 with 70+ percent of the tickets and 60+ percent of the handle in support of the line move. However, Zona’s played to the under at a 3-2-1 clip on the road with an average of 46.3 points scored.

Arizona Cardinals Week 15 Recap

The Arizona Cardinals delivered a dominant performance in their 30-17 win and NFL spread cover against the New England Patriots, improving to 7-7 SU to snap a poorly timed three-game losing streak. Despite losing linebackers Mack Wilson Sr. (concussion) and Jesse Luketa (thigh) within the first five plays, Arizona’s defense held firm, limiting the Patriots to 311 total yards, with nearly half coming in the fourth quarter. Right tackle Jonah Williams scored his first NFL touchdown in unusual fashion, recovering a Greg Dortch fumble in the end zone to give Arizona an early 10-0 lead. James Conner led the offensive charge with 110 rushing yards and two touchdowns, including a 1-yard score that extended the lead to 23-3 early in the fourth quarter. Kyler Murray was efficient, completing 23 of 30 passes for 224 yards, while Trey McBride caught nine passes for 87 yards. The Cardinals excelled on third downs, converting 10 of 15 attempts, which Murray credited as a key to their success. Arizona’s defense also made critical stops, including a goal-line stand in the third quarter. Chad Ryland contributed three field goals, and the Cardinals capitalized on a roughing-the-passer penalty to maintain momentum. With the win, Arizona remains on the fringe of playoff contention with only three chances remaining on the docket.

2024 Arizona Cardinals Schedule, Results & Record

Founded in 1920 as the Chicago Cardinals, the Arizona Cardinals have a storied history marked by periods of frustration and futility. While based in Chicago, the Cardinals often found themselves overshadowed by the Chicago Bears, winning only two championships before relocating to St. Louis in 1960. Most seasons during their Chicago tenure were marked by losing records.

Upon moving to St. Louis, the Cardinals were warmly received, but the pattern of losing persisted. During their time in St. Louis, the team made the playoffs only three times. Unable to secure a new stadium agreement, the franchise relocated to Arizona in 1988. The change of scenery didn't alter much, as the team's first playoff appearance didn't come until a decade later, when they were waxed by Randy Moss and the Minnesota Vikings in the Divisional Round.

In Arizona, the Cardinals have experienced their most successful era, although it remains modest compared to many other NFL franchises. Since 1998, the Cardinals have made the playoffs six times. The pinnacle of their success came in the 2008 season when they reached the Super Bowl for the first time in franchise history, ultimately losing to the Pittsburgh Steelers.

Arizona Cardinals Past Seasons (2000)

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